TC-99M NANOCOLLOID FOR THE SCINTIGRAPHIC ASSESSMENT OF INFLAMMATORY BOWEL-DISEASE IN THE COLON - ITS VALUE IN COMPARISON WITH INDIUM-111-LABELED GRANULOCYTES

被引：9

作者：

ARNDT, JW

VEER, AV

BLOK, D

GRIFFIOEN, G

VERSPAGET, HW

PENA, AS

LAMERS, CBHW

PAUWELS, EKJ

机构：

[1] Division of Nuclear Medicine (Department of Diagnostic Radiology), Department of Gastroenterology, University Hospital, Leiden

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 1991年 / 12卷 / 01期

关键词：

COLON RADIONUCLIDE IMAGING; COLON CROHNS DISEASE; COLON COLITIS; RADIONUCLIDE IMAGING COLON; RADIONUCLIDE IMAGING TC-99M-NANOCOLLOID;

D O I：

10.1016/0720-048X(91)90128-I

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The usefulness of 99m-Tc-nanocolloid for the assessment of localization and disease activity of colitis in patients suffering from inflammatory bowel disease (IBD) was investigated in 10 patients. Results of 99m-Tc-nanocolloid scintigraphy were compared with Indium-111 autologous granulocyte scintigraphy and the activity index according to Van Hees. In none of the patients a true positive result of the 99m-Tc-nanocolloid scintigraphy was encountered, while In-111-granulocyte scintigraphy was positive in 7 of 10 patients with active disease. Radioactivity became visible in the small bowel starting 2 h after injection of 99m-Tc-nanocolloid most likely because of excretion by the liver of degradation products of the radiopharmaceutical. The authors conclude that despite a previous communication 99m-Tc-nanocolloid cannot replace In-111-granulocytes for the assessment of IBD patients with active colitis.

引用

页码：30 / 34

页数：5

共 17 条

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