HYPERTRIGLYCERIDEMIA DURING LONG-TERM INTERFERON-ALPHA THERAPY - EFFICACY OF DIET AND GEMFIBROSIL TREATMENT - A CASE-REPORT

被引：14

作者：

BERRUTI, A ^{[1
]}

GORZEGNO, G ^{[1
]}

VITETTA, G ^{[1
]}

TAMPELLINI, M ^{[1
]}

DOGLIOTTI, L ^{[1
]}

机构：

[1] UNIV TORINO, OSPED SAN LUIGI GONZAGA, DIPARTIMENTO SCI CLIN & BIOL MED INTERNA ONCOL MED, I-10043 ORBASSANO, ITALY

来源：

TUMORI JOURNAL | 1992年 / 78卷 / 05期

关键词：

D O I：

10.1177/030089169207800515

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Interferon-alpha might increase triglyceride serum levels through the enhancement of hepatic lipogenesis and/or inhibition of the peripheral lipoprotein lipase. Hypertriglyceridemia during interferon-alpha therapy has been only recently described, mostly in patients with previous abnormalities of lipid metabolism. The authors report here a case of a 65-year-old male bearing advanced colon carcinoma who developed hypertriglyceridemia during long-term interferon-alpha treatment in association with 5 fluorouracil administration. Hypertriglyceridemia was maintained within acceptable levels, without adjusting the treatment plan, by an appropriate diet and gemfibrosil administration.

引用

页码：353 / 355

页数：3

共 20 条

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