ANTITUMOR ACTIVITY OF JUGLANS NIGRA [BLACK WALNUT) EXTRACTIVES

被引：37

作者：

BHARGAVA, UC

WESTFALL, BA

机构：

[1] School of Medicine, University of Missouri, Columbia, Missouri

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1968年 / 57卷 / 10期

关键词：

Acidic components; Juglans nigra—antitumor activity; Alkaloids; Antitumor compounds—Juglans nigra; Ellagic acid—antitumor activity; Juglone—antitumor activity;

D O I：

10.1002/jps.2600571009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Antitumor activity of compounds present in Juglans nigra were studied on spontaneous and/or transplanted tumors in mice. Ellagic acid, juglone, and isolated fractions (strong acids, weak acids, and alkaloids) were injected intraperitoneally for 9–12 days. The results showed that ellagic acid, juglone, and the “strong acids” fraction depressed the tumor growth rate significantly. Copyright © 1968 Wiley‐Liss, Inc., A Wiley Company

引用

页码：1674 / &

共 12 条

[1]

AUYONG T. K., 1963, TOXICON, V1, P235, DOI 10.1016/0041-0101(63)90005-9

[2]

BHARGAVA UC, 1967, FED PROC, V26, P737

[3]

CAIN B. F., 1963, NEW ZEALAND JOUR SCI, V6, P264

[4] STUDIES ON CATHARANTHUS LANCEUS (VINCA LANCEA) .1. ISOLATION OF LEUROSINE, PERIVINE, AND YOHIMBINE [J].