A MORPHOMETRIC STUDY OF THE HUMAN ENDOMETRIAL STROMA DURING THE PERIIMPLANTATION PERIOD

被引：13

作者：

DOCKERY, P

WARREN, MA

LI, TC

ROGERS, AW

COOKE, ID

MUNDY, J

机构：

[1] Department of Biomedical Science, University of Sheffield

[2] Department of Obstetrics and Gynaecology, University of Sheffield

[3] Harris Birthright Centre for Reproductive Medicine, Jessop Hospital for Women

来源：

HUMAN REPRODUCTION | 1990年 / 5卷 / 02期

关键词：

Morphometry; Stroma; Timed endometrial biopsy;

D O I：

10.1093/oxfordjournals.humrep.a137052

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

In this study we have examined the human endometrial stromal cell population in well-timed biopsies during the peri-implantation period, using traditional stereological techniques. This paper reports data obtained from 16 women of known fertility who underwent endometrial biopsies at known times after the luteinizing hormone (LH) surge (four each at LH + 2, LH + 4, LH + 6 and LH + 8). The average stromal cell nuclear diameter increased in size throughout the period of study (P < 0.01), with a significant decrease (P < 0.05) in the nuclear profile axial ratio. This suggests that the nuclei were increasing in size and becoming more rounded. There was a dramatic increase (P < 0.01) in the packing density between LH + 2 and LH + 6; this is likely to be due, at least in part, to the glands filling up with secretory products and so compressing the intervening stroma. A substantial decrease (P < 0.01) was seen in the packing density between LH + 6 and LH + 8. This corresponds to the time when stromal oedema is thought to be maximal. © 1990 Oxford University Press.

引用

页码：112 / 116

页数：5

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