AN IMPROVED TOTAL SYNTHESIS OF BLEOMYCIN

被引：32

作者：

SAITO, S ^{[1
]}

UMEZAWA, Y ^{[1
]}

YOSHIOKA, T ^{[1
]}

TAKITA, T ^{[1
]}

UMEZAWA, H ^{[1
]}

MURAOKA, Y ^{[1
]}

机构：

[1] NIPPON KAYAKU CO LTD,RES LABS,DIV PHARMACEUT,KITA KU,TOKYO 115,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1983年 / 36卷 / 01期

关键词：

D O I：

10.7164/antibiotics.36.92

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：92 / 95

页数：4

共 10 条

[1] SYNTHETIC STUDIES OF AMINO ACIDS BY USE OF COPPER COMPLEX .2. CONDENSATION REACTION OF N-PYRUVYLIDENEGLYCINATOCOPPER(II) COMPLEXES WITH VARIOUS ALDEHYDES [J].

ICHIKAWA, T ;

MAEDA, S ;

OKAMOTO, T ;

ARAKI, Y ;

ISHIDO, Y .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1971, 44 (10) :2779-+

[2] NEW AGENTS FOR TERTIARY BUTYLOXYCARBONYLATION AND PARA METHOXYBENZYL-OXYCARBONYLATION OF AMINO-ACIDS [J].

NAGASAWA, T ;

KUROIWA, K ;

NARITA, K ;

ISOWA, Y .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1973, 46 (04) :1269-1272

[3] THE STABILITY OF FUSED RINGS IN METAL CHELATES .2. COPPER(II) COMPLEXES OF SCHIFF BASES DERIVED FROM PYRUVIC ACID AND AMINO ACIDS OR DIAMINES [J].

NAKAHARA, A ;

YAMAMOTO, H ;

MATSUMOTO, H .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1964, 37 (08) :1137-1142

[4] STEREOSELECTIVE SYNTHESIS OF (2S,3S,4R)-4-AMINO-3-HYDROXY-2-METHYL-PENTANOIC ACID, AN AMINO-ACID CONSTITUENT OF BLEOMYCIN, BY ALDOL CONDENSATION [J].

NARITA, M ;

OTSUKA, M ;

KOBAYASHI, S ;

OHNO, M ;

UMEZAWA, Y ;

MORISHIMA, H ;

SAITO, SI ;

TAKITA, T ;

UMEZAWA, H .

TETRAHEDRON LETTERS, 1982, 23 (05) :525-528

[5] OXIDATIONS WITH MANGANESE DIOXIDE [J].

PAPADOPO.EP ;

JARRAR, A ;

ISSIDORI.CH .

JOURNAL OF ORGANIC CHEMISTRY, 1966, 31 (02) :615-&

[6] TOTAL SYNTHESIS OF BLEOMYCIN-A2 [J].

TAKITA, T ;

UMEZAWA, Y ;

SAITO, SI ;

MORISHIMA, H ;

NAGANAWA, H ;

UMEZAWA, H ;

TSUCHIYA, T ;

MIYAKE, T ;

KAGEYAMA, S ;

UMEZAWA, S ;

MURAOKA, Y ;

SUZUKI, M ;

OTSUKA, M ;

NARITA, M ;

KOBAYASHI, S ;

OHNO, M .

TETRAHEDRON LETTERS, 1982, 23 (05) :521-524

[7]

TAKITA T, 1981, PEPTIDES, P29

[8] SYNTHESIS OF THE PYRIMIDINE MOIETY OF BLEOMYCIN [J].

UMEZAWA, Y ;

MORISHIMA, H ;

SAITO, S ;

TAKITA, T ;

UMEZAWA, H ;

KOBAYASHI, S ;

OTSUKA, M ;

NARITA, M ;

OHNO, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (21) :6630-6631

[9] CHEMICAL STUDIES ON TUBERACTINOMYCIN .14. NOVEL SYNTHESIS OF DL-CAPREOMYCIDINE [J].

WAKAMIYA, T ;

MIZUNO, K ;

UKITA, T ;

TESHIMA, T ;

SHIBA, T .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1978, 51 (03) :850-854

[10]

YOSHIOKA T, 1977, THESIS U TOKYO, P151

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