A SODIUM-ACTIVATED POTASSIUM CURRENT IN INTACT VENTRICULAR MYOCYTES ISOLATED FROM THE GUINEA-PIG HEART

被引：26

作者：

RODRIGO, GC ^{[1
]}

CHAPMAN, RA ^{[1
]}

机构：

[1] UNIV BRISTOL,DEPT PHYSIOL,PK ROW,BRISTOL BS1 5LS,ENGLAND

来源：

EXPERIMENTAL PHYSIOLOGY | 1990年 / 75卷 / 06期

关键词：

D O I：

10.1113/expphysiol.1990.sp003465

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

A current generated by the Na‐activated K channel has been identified in whole cell currents recorded from isolated guinea‐pig ventricular myocytes. A partial activation of this current can be achieved near to the physiological range of intracellular sodium concentration [( Na+]i) when it contributes significantly to the global outward current. The decline of the Na‐activated K current, the lengthening of the action potential duration and the recovery of [Na+]i occur with a similar time course during recovery from Na loading. © 1990 The Physiological Society

引用

页码：839 / 842

页数：4

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