EXTRACELLULAR RECORDING IN NEURONAL NETWORKS WITH SUBSTRATE INTEGRATED MICROELECTRODE ARRAYS

被引：33

作者：

HAMMERLE, H

EGERT, U

MOHR, A

NISCH, W

机构：

[1] Naturwissenschaftliches und Medizinisches Institut an der Universitat Tubingen in Reutlingen, 72762 Reutlingen

来源：

BIOSENSORS & BIOELECTRONICS | 1994年 / 9卷 / 9-10期

关键词：

BIOELECTRONICS; MICROELECTRODE-ARRAY; NEURONAL NETWORK IN VITRO; EXTRACELLULAR RECORDING; RETINAL GANGLION CELLS IN VITRO; PHOTOSTIMULATION; CHICKEN;

D O I：

10.1016/0956-5663(94)80067-7

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A photolithographically produced array of 60 substrate-integrated microelectrodes was used for extracellular recording. Neuronal electrical activity was recorded from chicken retinal ganglion cells with or without stimulation by diffuse light. The retina was removed from chicken embryos of embryonic day 14-18. Only cells recorded from day 18 retina would react to photostimulation, increasing their activity when stimulated, corresponding to the developmental time course of photoreceptor differentiation.

引用

页码：691 / 696

页数：6

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