ORIGIN AND CONTROL OF MULTI-PEAK FORMATION IN THE ANALYSIS OF TRIMETHYLSILYL DERIVATIVES OF FLAVANONE AGLYCONES BY CAPILLARY COLUMN GAS-CHROMATOGRAPHY

Trimethylsilyl derivatives of flavanone aglycones give double peaks in their gas chromatograms. The origin of these peaks, from an isomerization between the flavanones and their corresponding chalcones, has been examined using gas chromatography-mass spectrometry and UV spectrophotometry. The effects of derivatization temperature, time and capillary column injection technique on the rate of the interconversion have been defined.