NITRATION PRODUCTS OF SUBSTITUTED 1,3-DIHYDRO-5-PHENYL-2H-1,4-BENZODIAZEPIN-2-ONES

被引：6

作者：

FRYER, RI ^{[1
]}

GU, ZQ ^{[1
]}

TODARO, L ^{[1
]}

机构：

[1] HOFFMANN LA ROCHE INC,DEPT CHEM RES,NUTLEY,NJ 07110

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 05期

关键词：

D O I：

10.1002/jhet.5570280508

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly substituted, novel, 1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-ones were obtained by direct nitration of the corresponding mono- or di-substituted 5-phenyl-1,4-benzodiazepines. Substituent effects and the orientation of aromatic substituents in the nitration products are discussed. The single-crystal X-ray structural data for one of these products, 18, is given.

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页码：1203 / 1208

页数：6

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