CYTOTOXIC AND ANTIBACTERIAL LABDANE-TYPE DITERPENES FROM THE AERIAL PARTS OF CISTUS-INCANUS SUBSP CRETICUS

被引：96

作者：

CHINOU, I

DEMETZOS, C

HARVALA, C

ROUSSAKIS, C

VERBIST, JF

机构：

[1] PANEPISTIMIOPOLIS ZOGRAFOU,DEPT PHARM,PHARMACOGNOSY LAB,GR-15771 ZOGRAFOS,GREECE

[2] UNIV NANTES,DEPT PHARMACOGNOSIE,F-44100 NANTES,FRANCE

来源：

PLANTA MEDICA | 1994年 / 60卷 / 01期

关键词：

CISTUS; CISTACEAE; LABDANE DITERPENES; CYTOTOXICITY; ANTIBACTERIAL ACTIVITY;

D O I：

10.1055/s-2006-959403

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Seven labdane-type diterpenoids were isolated from the leaves of Cistus incanus subsp. creticus; their structures were established by spectroscopic means. AU compounds were tested in vitro for their cytotoxicity against three cell line systems: KB, P-388; and NSCLC-NG. Their antibacterial and antifungal activities were tested against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosae, Enterobacter cloacae, Escherichia coli, Klebsiella pneumonia, Torulopsis glabrata, Saccharomyces cerevisiae, and Candida albicans as well.

引用

页码：34 / 36

页数：3

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