TRANSFER-RNA-M(1)G METHYLTRANSFERASE INTERACTIONS - TOUCHING BASES WITH STRUCTURE

被引：12

作者：

HOLMES, WM

ANDRAOSSELIM, C

REDLAK, M

机构：

[1] Department of Microbiology/Immunology, Virginia Commonwealth University, Medical College of Virginia, Richmond, VA 23298

来源：

BIOCHIMIE | 1995年 / 77卷 / 1-2期

关键词：

TRANSFER-RNA; METHYLATION; RECOGNITION;

D O I：

10.1016/0300-9084(96)88105-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

m(1)G methyltransferase of Escherichia coli is being examined with regard to how specific tRNA substrates are recognized. This enzyme appears to require the entire tRNA structure of optimal activity. Recognition may require specific base contacts as well as phosphate backbone structures embodied in the tRNA structure.

引用

页码：62 / 65

页数：4

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