KRAS CODON-12 MUTATIONS OCCUR VERY FREQUENTLY IN PANCREATIC ADENOCARCINOMAS

被引：611

作者：

SMIT, VTHBM

BOOT, AJM

SMITS, AMM

FLEUREN, GJ

CORNELISSE, CJ

BOS, JL

机构：

[1] STATE UNIV LEIDEN, MOLEC CARCINOGENESIS LAB, POB 9305, 2300 RA LEIDEN, NETHERLANDS

[2] STATE UNIV LEIDEN, DEPT PATHOL, 2300 RA LEIDEN, NETHERLANDS

来源：

NUCLEIC ACIDS RESEARCH | 1988年 / 16卷 / 16期

关键词：

D O I：

10.1093/nar/16.16.7773

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：7773 / 7782

页数：10

共 27 条

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[2] MOST HUMAN CARCINOMAS OF THE EXOCRINE PANCREAS CONTAIN MUTANT C-K-RAS GENES
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[3] BOS JL, 1987, BLOOD, V69, P1237
[4] PREVALENCE OF RAS GENE-MUTATIONS IN HUMAN COLORECTAL CANCERS
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[5] GENETIC MECHANISMS IN TUMOR INITIATION AND PROGRESSION .10. THE RAS GENE FAMILY AND HUMAN CARCINOGENESIS
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[6] 3 DIFFERENT MUTATIONS IN CODON-61 OF THE HUMAN N-RAS GENE DETECTED BY SYNTHETIC OLIGONUCLEOTIDE HYBRIDIZATION
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[J]. NUCLEIC ACIDS RESEARCH, 1984, 12 (23) : 9155 - 9163
[7] THE CYTOPLASMIC PROTEIN GAP IS IMPLICATED AS THE TARGET FOR REGULATION BY THE RAS GENE-PRODUCT
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[J]. NATURE, 1988, 332 (6164) : 548 - 551
[8] ANALYSIS OF RAS GENE-MUTATIONS IN ACUTE MYELOID-LEUKEMIA BY POLYMERASE CHAIN-REACTION AND OLIGONUCLEOTIDE PROBES
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SAIKI, RK
ERLICH, HA
MCCORMICK, F
MARSHALL, CJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (05) : 1629 - 1633
[9] DETECTION OF HIGH-INCIDENCE OF K-RAS ONCOGENES DURING HUMAN-COLON TUMORIGENESIS
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PERUCHO, M
[J]. NATURE, 1987, 327 (6120) : 298 - 303
[10] GENETIC MECHANISMS IN TUMOR INITIATION AND PROGRESSION .4. MUTATIONAL ACTIVATION OF ONCOGENES IN ANIMAL-MODEL SYSTEMS OF CARCINOGENESIS
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[J]. MUTATION RESEARCH, 1987, 185 (03): : 293 - 308

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