IMMUNOLOGICAL IDENTIFICATION OF NA/CA EXCHANGE PROTEIN IN RAT-BRAIN SYNAPTIC PLASMA-MEMBRANE

被引：23

作者：

YIP, RK

BLAUSTEIN, MP

PHILIPSON, KD

机构：

[1] UNIV MARYLAND,SCH MED,DEPT PHYSIOL,655 W BALTIMORE ST,BALTIMORE,MD 21201

[2] UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,LOS ANGELES,CA 90024

[3] UNIV CALIF LOS ANGELES,SCH MED,DEPT PHYSIOL,LOS ANGELES,CA 90024

[4] UNIV CALIF LOS ANGELES,SCH MED,CARDIOVASC RES LAB,LOS ANGELES,CA 90024

来源：

NEUROSCIENCE LETTERS | 1992年 / 136卷 / 01期

关键词：

NA/CA EXCHANGER; CARDIAC; SARCOLEMMA; SYNAPTIC; ANTIBODY; IMMUNOBLOT;

D O I：

10.1016/0304-3940(92)90663-R

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Polyclonal antibodies raised against partially purified dog cardiac Na/Ca exchanger react with cardiac sarcolemmal proteins of 160, 120 and 70 kDa on SDS-PAGE. Using the same specific antiserum, we detected three prominent immunoreactive bands of about 150, 120 and 70 kDa on immunoblots with rat forebrain synaptic plasma membrane proteins. These data indicate that the Na/Ca exchange protein in rat brain synaptic plasma membrane is structurally and antigenically similar to the exchange protein in dog cardiac sarcolemma.

引用

页码：123 / 126

页数：4

共 21 条

[1] BIOCHEMICAL AND MOLECULAR CHARACTERIZATION OF THE SODIUM-CALCIUM EXCHANGER FROM BOVINE ROD PHOTORECEPTORS [J].