ABNORMAL AMBIENT GLUCOSE-LEVELS INHIBIT PROTEOGLYCAN CORE PROTEIN GENE-EXPRESSION AND REDUCE PROTEOGLYCAN ACCUMULATION DURING CHONDROGENESIS - POSSIBLE MECHANISM FOR TERATOGENIC EFFECTS OF MATERNAL DIABETES

被引：36

作者：

LEONARD, CM

BERGMAN, M

FRENZ, DA

MACREERY, LA

NEWMAN, SA

机构：

[1] NEW YORK MED COLL,RACHMIEL LEVINE DIABET CTR,VALHALLA,NY 10595

[2] NEW YORK MED COLL,DEPT CELL BIOL & ANAT,VALHALLA,NY 10595

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 24期

关键词：

D O I：

10.1073/pnas.86.24.10113

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：10113 / 10117

页数：5

共 56 条

[1] STAGE-RELATED CAPACITY FOR LIMB CHONDROGENESIS IN CELL-CULTURE [J].

AHRENS, PB ;

SOLURSH, M ;

REITER, RS .

DEVELOPMENTAL BIOLOGY, 1977, 60 (01) :69-82

[2] METICULOUS CONTROL OF DIABETES DURING ORGANOGENESIS PREVENTS CONGENITAL LUMBOSACRAL DEFECTS IN RATS [J].

BAKER, L ;

EGLER, JM ;

KLEIN, SH ;

GOLDMAN, AS .

DIABETES, 1981, 30 (11) :955-959

[3] TRANS-PLACENTAL PASSAGE OF INSULIN COMPLEXED TO ANTIBODY [J].

BAUMAN, WA ;

YALOW, RS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (07) :4588-4590

[4]

BERGMAN M, 1986, NEW YORK STATE J MED, V86, P174

[5] ASSAY FOR NANOGRAM QUANTITIES OF DNA IN CELLULAR HOMOGENATES [J].

BRUNK, CF ;

JONES, KC ;

JAMES, TW .

ANALYTICAL BIOCHEMISTRY, 1979, 92 (02) :497-500

[6] EMBRYOTOXIC EFFECTS OF BRIEF MATERNAL INSULIN-HYPOGLYCEMIA DURING ORGANOGENESIS IN THE RAT [J].

BUCHANAN, TA ;

SCHEMMER, JK ;

FREINKEL, N .

JOURNAL OF CLINICAL INVESTIGATION, 1986, 78 (03) :643-649

[7] INCREASED EXPRESSION OF BASEMENT-MEMBRANE COMPONENTS IN HUMAN-ENDOTHELIAL CELLS CULTURED IN HIGH GLUCOSE [J].

CAGLIERO, E ;

MAIELLO, M ;

BOERI, D ;

ROY, S ;

LORENZI, M .

JOURNAL OF CLINICAL INVESTIGATION, 1988, 82 (02) :735-738

[8] TERATOGENIC EFFECTS OF EXCESS GLUCOSE ON HEAD-FOLD RAT EMBRYOS IN CULTURE [J].

COCKROFT, DL ;

COPPOLA, PT .

TERATOLOGY, 1977, 16 (02) :141-146

[9]

COHEN CD, 1986, DIABETES, V37, pA236

[10]

DEUCHAR EM, 1977, J EMBRYOL EXP MORPH, V41, P93

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