OKADAXANTHIN, A NOVEL C-50-CAROTENOID FROM A BACTERIUM, PSEUDOMONAS SP KK10206C ASSOCIATED WITH MARINE SPONGE, HALICHONDRIA-OKADAI

被引：28

作者：

MIKI, W

OTAKI, N

YOKOYAMA, A

IZUMIDA, H

SHIMIDZU, N

机构：

[1] Shimizu Laboratories, Marine Biotechnology Institute (MBI), Shizuoka, 424, 1900 Sodeshi, Shimizu

来源：

EXPERIENTIA | 1994年 / 50卷 / 07期

关键词：

CAROTENOID; MARINE SPONGE; HALICHONDRIA OKADAI; SPONGE ASSOCIATED BACTERIA; PSEUDOMONAS SP; OKADAXANTHIN; SINGLET OXYGEN QUENCHER;

D O I：

10.1007/BF01952874

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

To study the origins of biologically active substances in marine sponges, a carotenoid produced by a marine bacterium, Pseudomonas sp. strain number KK10206C, which was associated with a marine sponge, Halichondra akadai, was investigated. A visible absorption spectrum-guided isolation procedure led to the isolation of a novel C-50-carotenoid, okadaxanthin. Its structure, 2,2'-bis(4-hydroxy-2-methyl-2-butenyl)-epsilon,epsilon-carotene, was elucidated mainly by spectroscopic methods. Okadexanthin turned out to be a potent singlet oxygen quencher, approximately 10 times as strong as alpha-tocopherol.

引用

页码：684 / 686

页数：3

共 7 条

[1] C-45 CAROTENOID AND C-50 CAROTENOID .6. SYNTHESIS OF AN OPTICALLY-ACTIVE CYCLIC C-20-BUILDING BLOCK AND OF DECAPRENOXANTHIN (= (2R,6R,2'R,6'R)-2,2'-BIS(4-HYDROXY-3-METHYLBUT-2-ENYL)-EPSILON,EPSILON-CAROTENE) [J].