HUMAN FOLLICULAR FLUIDS CONTAIN TISSUE MACROPHAGES

被引：130

作者：

LOUKIDES, JA

LOY, RA

EDWARDS, R

HONIG, J

VISINTIN, I

POLAN, ML

机构：

[1] STANFORD UNIV, MED CTR, SCH MED, DEPT GYNECOL & OBSTET, STANFORD, CA 94305 USA

[2] YALE UNIV, SCH MED, DEPT OBSTET & GYNECOL, REPROD ENDOCRINOL SECT, NEW HAVEN, CT 06510 USA

[3] YALE UNIV, SCH MED, DEPT PATHOL, NEW HAVEN, CT 06510 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1990年 / 71卷 / 05期

关键词：

D O I：

10.1210/jcem-71-5-1363

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Tissue cells obtained from the follicular fluids of women undergoing in vitro fertilization and embryo transfer were found to contain interleukin-lβ mRNA by Northern analysis. Since macrophages are known to produce interleukin-1β, We examined the follicular fluids of 20 women undergoing in vitro fertilization as well as tissue sections of normal human ovary for the presence of macrophages and monocytes. Although granulosa-luteal cells predominate in follicular fluid, we found that resident macrophages and monocytes comprise 5–15% of human follicular tissue cells. In addition, we observed that macrophages are present in the human ovarian follicle as well as in the corpus luteum. © 1990 by The Endocrine Society.

引用

页码：1363 / 1367

页数：5

共 12 条

[1]

ADASHI EY, 1989, ENDOCRINOLOGY, V124, P2043

[2] INCREASED PLASMA INTERLEUKIN-1 ACTIVITY IN WOMEN AFTER OVULATION [J].