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GUANYLATE-CYCLASE IN HUMAN PLATELETS WITH DIFFERENT AGGREGABILITY

被引：14
作者：
CHIRKOV, YY
TYSHCHUK, IA
SEVERINA, IS
机构：
[1] Institute of Biological and Medical Chemistry, USSR Academy of Medical Sciences, Moscow, 119832
来源：
EXPERIENTIA | 1990年 / 46卷 / 07期
关键词：
diabetes mellitus; Guanylate cyclase; human platelets; platelet aggregation;
D O I：
10.1007/BF01939938
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The activity of human platelet guanylate cyclase, and the activation of the enzyme by sodium nitroprusside were decreased in platelets with increased aggregability; these platelets were obtained from diabetes mellitus patients. Anomalies in guanylate cyclase activity and ADP-induced aggregation were more pronounced in platelets from subjects with type II than those with type I diabetes. © 1990 Birkhäuser Verlag Basel.
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页码：697 / 699
页数：3
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