POTASSIUM CHANNELS IN AIRWAY SMOOTH-MUSCLE - A TALE OF 2 CHANNELS

被引：54

作者：

KOTLIKOFF, MI ^{[1
]}

机构：

[1] UNIV PENN,SCH MED,DEPT MED,PHILADELPHIA,PA 19104

来源：

PHARMACOLOGY & THERAPEUTICS | 1993年 / 58卷 / 01期

关键词：

D O I：

10.1016/0163-7258(93)90064-K

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Potassium channels are an important determinant of smooth muscle excitability and force generation. Two potassium channels have been fully described in airway smooth muscle: large conductance, calcium-activated potassium channels and voltage-dependent delayed rectifier channels. This article will review the biophysics and pharmacology of these channels and discuss what is currently known with respect to their regulation and physiological significance.

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页码：1 / 12

页数：12

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