LIMITATIONS OF DARWINIAN SELECTION IN A FINITE POPULATION

被引：16

作者：

KIMURA, M

机构：

[1] National Institute of Genetics

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1995年 / 92卷 / 06期

关键词：

SUBSTITUTION LOAD; NEUTRAL THEORY; NATURAL SELECTION; COST OF NATURAL SELECTION;

D O I：

10.1073/pnas.92.6.2343

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In a finite population, the rate at which favorable mutations at several loci can evolve simultaneously is limited by the reproductive capacity of the species and the effective population number. The number of such loci is given by n < - (N-e/2) ln(1 - L(T)), in which N-e is the effective population number and L(T) is the ''substitution load'' (roughly, the reproductive excess available for positive selection). If L(T) = 0.1, as seems reasonable for large mammals, n < 0.05N(e).

引用

页码：2343 / 2344

页数：2