GENETIC-ANALYSIS OF THE MOLECULAR-BASIS FOR BETA-ADRENERGIC-RECEPTOR SUBTYPE SPECIFICITY

被引：29

作者：

DIXON, RAF ^{[1
]}

HILL, WS ^{[1
]}

CANDELORE, MR ^{[1
]}

RANDS, E ^{[1
]}

DIEHL, RE ^{[1
]}

MARSHALL, MS ^{[1
]}

SIGAL, IS ^{[1
]}

STRADER, CD ^{[1
]}

机构：

[1] MERCK SHARP & DOHME LTD,DEPT MOLEC PHARMACOL & BIOCHEM,RAHWAY,NJ 07065

来源：

PROTEINS-STRUCTURE FUNCTION AND GENETICS | 1989年 / 6卷 / 03期

关键词：

D O I：

10.1002/prot.340060309

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：267 / 274

页数：8

共 18 条

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[2] CLONING OF THE GENE AND CDNA FOR MAMMALIAN BETA-ADRENERGIC-RECEPTOR AND HOMOLOGY WITH RHODOPSIN [J].

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[3] STRUCTURAL FEATURES REQUIRED FOR LIGAND-BINDING TO THE BETA-ADRENERGIC-RECEPTOR [J].

DIXON, RAF ;

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EMBO JOURNAL, 1987, 6 (11) :3269-3275

[4] STRUCTURE-FUNCTION ANALYSIS OF THE BETA-ADRENERGIC-RECEPTOR [J].

DIXON, RAF ;

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STRADER, CD .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1988, 53 :487-497

[5] LIGAND-BINDING TO THE BETA-ADRENERGIC-RECEPTOR INVOLVES ITS RHODOPSIN-LIKE CORE [J].

DIXON, RAF ;

SIGAL, IS ;

RANDS, E ;

CANDELORE, MR ;

BLAKE, AD ;

STRADER, CD .

NATURE, 1987, 326 (6108) :73-77

[6]

FREILLE T, 1987, P NATL ACAD SCI USA, V84, P7920

[7] STRUCTURAL BASIS OF BETA-ADRENERGIC-RECEPTOR SUBTYPE SPECIFICITY STUDIED WITH CHIMERIC BETA-1-ADRENERGIC BETA-2-ADRENERGIC RECEPTORS [J].

FRIELLE, T ;

DANIEL, KW ;

CARON, MG ;

LEFKOWITZ, RJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (24) :9494-9498

[8] CDNA FOR THE HUMAN BETA-2-ADRENERGIC RECEPTOR - A PROTEIN WITH MULTIPLE MEMBRANE-SPANNING DOMAINS AND ENCODED BY A GENE WHOSE CHROMOSOMAL LOCATION IS SHARED WITH THAT OF THE RECEPTOR FOR PLATELET-DERIVED GROWTH-FACTOR [J].

KOBILKA, BK ;

DIXON, RAF ;

FRIELLE, T ;

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BOLANOWSKI, MA ;

SIGAL, IS ;

YANGFENG, TL ;

FRANCKE, U ;

CARON, MG ;

LEFKOWITZ, RJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (01) :46-50

[9] CLONING, SEQUENCING, AND EXPRESSION OF THE GENE CODING FOR THE HUMAN-PLATELET ALPHA-2-ADRENERGIC RECEPTOR [J].

KOBILKA, BK ;

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REGAN, JW .

SCIENCE, 1987, 238 (4827) :650-656

[10] ADENYLATE CYCLASE-COUPLED BETA-ADRENERGIC RECEPTORS - STRUCTURE AND MECHANISMS OF ACTIVATION AND DESENSITIZATION [J].

LEFKOWITZ, RJ ;

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CARON, MG .

ANNUAL REVIEW OF BIOCHEMISTRY, 1983, 52 :159-186

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