INVITRO ACTIVITY OF CP-99,219, A NEW FLUOROQUINOLONE, AGAINST CLINICAL ISOLATES OF GRAM-POSITIVE BACTERIA

被引：126

作者：

ELIOPOULOS, GM

KLIMM, K

ELIOPOULOS, CT

FERRARO, MJ

MOELLERING, RC

机构：

[1] HARVARD UNIV,SCH MED,BOSTON,MA 02115

[2] MASSACHUSETTS GEN HOSP,DEPT MED,BOSTON,MA 02114

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 02期

关键词：

D O I：

10.1128/AAC.37.2.366

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activity of the fluoroquinolone CP-99,219 against gram-positive bacteria was compared with those of five other antimicrobial agents. Against ciprofloxacin-susceptible staphylococci and against streptococci, MICs were less-than-or-equal-to 0.12 and less-than-or-equal-to 0.5 mug/ml, respectively. CP-99,219 was also more active than ciprofloxacin against ciprofloxacin-resistant staphylococci, most enterococci, Leuconostoc spp., and lactobacilli.

引用

页码：366 / 370

页数：5

共 9 条

[1] COMPARATIVE INVITRO ACTIVITY OF WIN-57273, A NEW FLUOROQUINOLONE ANTIMICROBIAL AGENT
ELIOPOULOS, GM
KLIMM, K
RICE, LB
FERRARO, MJ
MOELLERING, RC
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1990, 34 (06) : 1154 - 1159
[2] INVITRO ACTIVITY OF SCH-29482 IN COMPARISON WITH OTHER ORAL ANTIBIOTICS
ELIOPOULOS, GM
GARDELLA, A
MOELLERING, RC
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1982, 9 : 143 - 152
[3] ELIOPOULOS GM, 1992, 32ND INT C ANT AG CH
[4] ELIOPOULOS GM, 1992, IN PRESS QUINOLONE A
[5] MULTICENTER EVALUATION OF THE INVITRO ACTIVITIES OF 3 NEW QUINOLONES, SPARFLOXACIN, CI-960, AND PD-131,628, COMPARED WITH THE ACTIVITY OF CIPROFLOXACIN AGAINST 5,252 CLINICAL BACTERIAL ISOLATES
FUCHS, PC
BARRY, AL
PFALLER, MA
ALLEN, SD
GERLACH, EH
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1991, 35 (04) : 764 - 766
[6] COMPARISON OF ENTEROCOCCUS-RAFFINOSUS WITH ENTEROCOCCUS-AVIUM ON THE BASIS OF PENICILLIN SUSCEPTIBILITY, PENICILLIN-BINDING PROTEIN-ANALYSIS, AND HIGH-LEVEL AMINOGLYCOSIDE RESISTANCE
GRAYSON, ML
ELIOPOULOS, GM
WENNERSTEN, CB
RUOFF, KL
KLIMM, K
SAPICO, FL
BAYER, AS
MOELLERING, RC
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1991, 35 (07) : 1408 - 1412
[7] COMPARATIVE INVITRO ACTIVITY OF PD-127391, A NEW FLUOROQUINOLONE AGENT, AGAINST SUSCEPTIBLE AND RESISTANT CLINICAL ISOLATES OF GRAM-POSITIVE COCCI
MIRANDA, AG
WANGER, AR
SINGH, KV
MURRAY, BE
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1992, 36 (06) : 1325 - 1328
[8] TRANSFERABLE BETA-LACTAMASE - A NEW MECHANISM FOR INVITRO PENICILLIN RESISTANCE IN STREPTOCOCCUS-FAECALIS
MURRAY, BE
MEDERSKISAMAROJ, B
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1983, 72 (03) : 1168 - 1171
[9] RAPID DISSEMINATION OF BETA-LACTAMASE PRODUCING, AMINOGLYCOSIDE-RESISTANT ENTEROCOCCUS-FAECALIS AMONG PATIENTS AND STAFF ON AN INFANT TODDLER SURGICAL WARD
RHINEHART, E
SMITH, NE
WENNERSTEN, C
GORSS, E
FREEMAN, J
ELIOPOULOS, GM
MOELLERING, RC
GOLDMANN, DA
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (26) : 1814 - 1818

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