SYNTHESIS OF 13,14-DEHYDROPROSTACYCLIN METHYL-ESTER - POTENT INHIBITOR OF PLATELET-AGGREGATION

被引：61

作者：

FRIED, J

BARTON, J

机构：

[1] UNIV CHICAGO,DEPT CHEM,CHICAGO,IL 60637

[2] UNIV CHICAGO,BEN MAY LAB CANC RES,CHICAGO,IL 60637

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1977年 / 74卷 / 06期

关键词：

D O I：

10.1073/pnas.74.6.2199

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：2199 / 2203

页数：5

共 10 条

[1] CHAPNICK BM, 1976, J PHARMACOL EXP THER, V196, P44
[2] FRIED J, 1976, ADV PROSTAG THROMB R, V1, P183
[3] SYNTHESIS AND BIOLOGICAL EFFECTS OF 13-DEHYDRO DERIVATIVES OF NATURAL PROSTAGLANDIN-F 2ALPHA AND E2 AND THEIR 15-EPI ENANTIOMERS
FRIED, J
LIN, CH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (04) : 429 - 430
[4] ARTERIAL-WALLS ARE PROTECTED AGAINST DEPOSITION OF PLATELET THROMBI BY A SUBSTANCE (PROSTAGLANDIN-X) WHICH THEY MAKE FROM PROSTAGLANDIN ENDOPEROXIDES
GRYGLEWSKI, RJ
BUNTING, S
MONCADA, S
FLOWER, RJ
VANE, JR
[J]. PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1976, 12 (05) : 685 - 713
[5] THROMBOXANES - NEW GROUP OF BIOLOGICALLY-ACTIVE COMPOUNDS DERIVED FROM PROSTAGLANDIN ENDOPEROXIDES
HAMBERG, M
SVENSSON, J
SAMUELSSON, B
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (08) : 2994 - 2998
[6] CHEMICAL-STRUCTURE OF PROSTAGLANDIN-X (PROSTACYCLIN)
JOHNSON, RA
MORTON, DR
KINNER, JH
GORMAN, RR
MCGUIRE, JC
SUN, FF
WHITTAKER, N
BUNTING, S
SALMON, J
MONCADA, S
VANE, JR
[J]. PROSTAGLANDINS, 1976, 12 (06): : 915 - 928
[7] ENZYME ISOLATED FROM ARTERIES TRANSFORMS PROSTAGLANDIN ENDOPEROXIDES TO AN UNSTABLE SUBSTANCE THAT INHIBITS PLATELET-AGGREGATION
MONCADA, S
GRYGLEWSKI, R
BUNTING, S
VANE, JR
[J]. NATURE, 1976, 263 (5579) : 663 - 665
[8] NOVEL PROSTAGLANDIN DERIVATIVE FORMED FROM ARACHIDONIC ACID BY RAT STOMACH HOMOGENATES
PACEASCIAK, C
WOLFE, LS
[J]. BIOCHEMISTRY, 1971, 10 (20) : 3657 - +
[9] ISOLATION, STRUCTURE, AND BIOSYNTHESIS OF 6-KETO-PROSTAGLANDIN-F1-ALPHA IN RAT STOMACH
PACEASCIAK, C
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (08) : 2348 - 2349
[10] PACEASCIAK C, 1970, CHEM COMMUN, P1234

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