SYNOVITIS IN ANGIOIMMUNOBLASTIC LYMPHADENOPATHY WITH DYSPROTEINEMIA SIMULATING RHEUMATOID-ARTHRITIS

被引：15

作者：

BOUMPAS, DT

WHEBY, MS

JAFFE, ES

STEINBERG, AD

KLIPPEL, JH

BALOW, JE

机构：

[1] UNIV VIRGINIA,DEPT MED,CHARLOTTESVILLE,VA 22903

[2] NCI,PATHOL LAB,BETHESDA,MD 20205

[3] NIAMSD,ARTHRIT & RHEUMATISM BRANCH,BETHESDA,MD

来源：

ARTHRITIS AND RHEUMATISM | 1990年 / 33卷 / 04期

关键词：

D O I：

10.1002/art.1780330417

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

We describe a patient with angioimmunoblastic lymphadenopathy with dysproteinemia who developed a symmetric, rheumatoid‐like, peripheral polyarthritis. Radiographs of the involved joints revealed soft tissue swelling without erosions or cartilage loss. Rheumatoid factor and fluorescent antinuclear antibodies were negative, and C‐reactive protein and erythrocyte sedimentation rate were normal. Synovial fluid analysis showed an inflammatory effusion (white blood cell count of 3,500/mm3, with 76% polymorphonuclear leukocytes). A closed synovial biopsy of the wrist revealed a mononuclear infiltrate consistent with angioimmunoblastic lymphadenopathy with dysproteinemia. Monthly parenteral chemotherapy treatment with high‐dose methyl‐prednisolone and cyclophosphamide resulted in remission of all manifestations of disease, including arthritis. Copyright © 1990 American College of Rheumatology

引用

页码：578 / 582

页数：5

共 14 条

[1]

MYCOSIS-FUNGOIDES WITH POLYARTHRITIS [J].