RECOMBINANT FACTOR-VIIA IN AN INFANT WITH HEMOPHILIA-A AND INHIBITORS

被引：7

作者：

TENGBORN, L

KJELLMAN, B

ELFSTRAND, PO

BAGENHOLM, T

机构：

[1] CENT HOSP SKOVDE,DEPT PAEDIAT DIS,SKOVDE,SWEDEN

[2] FAC ODONTOL GOTEBORG,DEPT ORAL SURG,GOTHENBURG,SWEDEN

[3] SAHLGRENS UNIV HOSP,COAGULAT DISORDERS SECT,S-41345 GOTHENBURG,SWEDEN

来源：

ACTA PAEDIATRICA | 1992年 / 81卷 / 6-7期

关键词：

ANTIBODIES; HEMOPHILIA; RECOMBINANT FACTOR-VIIA;

D O I：

10.1111/j.1651-2227.1992.tb12298.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Post-traumatic bleeding from the gingiva in a 16-month-old boy with severe haemophilia A did not stop after treatment with factor VIII concentrate and tranexamic acid, and it was demonstrated that he had developed antibodies to factor VIII. Treatment with recombinant factor VIIa 60-90-mu-g/kg body weight four to eight times daily, together with local measures, stopped the bleeding and no complications were seen.

引用

页码：566 / 567

页数：2

共 7 条

[1] INTRAVASCULAR COAGULATION WITH USE OF HUMAN PROTHROMBIN COMPLEX CONCENTRATES [J].