BONE-MARROW TRANSPLANT FROM FATHER TO SON AND SUBSEQUENT GRAFT FROM SON TO FATHER

被引：6

作者：

POWLES, RL ^{[1
]}

PARIKH, PM ^{[1
]}

HELENGLASS, G ^{[1
]}

ABOUD, HH ^{[1
]}

SMITH, CL ^{[1
]}

MRAZEK, IA ^{[1
]}

SHEPHERD, V ^{[1
]}

MILLIKEN, ST ^{[1
]}

TRELEAVEN, J ^{[1
]}

SHARROCK, C ^{[1
]}

FEARY, SW ^{[1
]}

MELLER, ST ^{[1
]}

LAWLER, S ^{[1
]}

机构：

[1] ST GEORGE HOSP,SCH MED,DIV IMMUNOL,LONDON,ENGLAND

来源：

LANCET | 1990年 / 335卷 / 8696期

关键词：

D O I：

10.1016/0140-6736(90)91065-I

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An 11-year-old boy with acute myeloblastic leukaemia in first remission received an allogeneic mismatched bone-marrow transplant (BMT) from his father in 1979; subsequent HLA typing showed that his haemopoietic system had been repopulated by the donor cells. In 1986 hypereosinophilic syndrome, secondary to a T-cell lymphocytic lymphoma, developed in the father, then aged 45 years. A full haematological remission was obtained by means of standard acute lymphoblastic leukaemia treatment. He then received melphalan, total body irradiation, and a BMT from his son. Graft-versus-host disease was transient in both patients, and father and son remain well and disease-free 20 months and 10 years, respectively, after BMT. © 1990.

引用

页码：999 / 1000

页数：2

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