MINOCYCLINE-INDUCED PNEUMONITIS WITH BILATERAL HILAR LYMPHADENOPATHY AND PLEURAL EFFUSION

被引:22
作者
BANDO, T
FUJIMURA, M
NODA, Y
HIROSE, J
OHTA, G
MATSUDA, T
机构
[1] Third Department of Internal Medicine, School of Medicine, , Kanazawa University, Kanazawa, 920
[2] Third Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa
[3] Department of Internal Medicine, Kanazawa
[4] Radiology, Uozu
[5] Pathology, Toyama Rosai Hospital, Uozu
关键词
DRUG-INDUCED PULMONARY DISEASE; PULMONARY INFILTRATES WITH EOSINOPHILIA; PROVOCATION TEST;
D O I
10.2169/internalmedicine.33.177
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 65-year-old man developed respiratory failure with diffuse interstitial shadow, bilateral pleural effusion, and bilateral hilar lymphadenopathy on chest X-ray and CT, after intravenous administration of minocycline. Corticosteroid therapy was effective. The findings from bronchoalveolar lavage (BAL) and transbronchial lung biopsy were compatible with eosinophilic pneumonia. Provocation test supported this diagnosis, but the lymphocyte stimulation test was negative. A review of the literature and the diagnoses of drug-induced pulmonary diseases are discussed.
引用
收藏
页码:177 / 179
页数:3
相关论文
共 12 条
  • [1] Rosenow E.C., The spectrum of drug-induced pulmonary disease, Ann Intern Med, 77, (1972)
  • [2] Cooper J.A.D., White D.A., Matthay R.A., Drug-induced pulmonary disease. Part 1: Cytotoxic drugs, Am Rev Respir Dis, 133, (1986)
  • [3] Cooper J.A.D., White D.A., Matthay R.A., Drug-induced pulmonary disease. Part 2: Noncytotoxic drugs, Am Rev Respir Dis, 133, (1986)
  • [4] Ho D., Tashkin D.P., Bein M.E., Sharma O., Pulmonary infiltrates with eosinophilia associated with tetracycline, Chest, 76, (1979)
  • [5] Warrington R.J., Tse K.S., Gorski B.A., Schwenk R., Sehon A.H., Evaluation of isoniazid-associated hepatitis by immunological tests, Clin Exp Immunol, 32, (1978)
  • [6] Heitzman E.R., Lymphadenopathy related to anticonvulsant therapy, Radiology, 89, (1967)
  • [7] Cullinan S.A., Bower G.C., Acute pulmonary hypersensitivity to carbamazepine, Chest, 68, (1975)
  • [8] Editorial. Acute eosinophilic pneumonia, Lancet, 335, (1990)
  • [9] Yokoyama A., Mizushima Y., Suzuki H., Arai N., Kitagawa M., Yano S., Acute eosinophilic pneumonia induced by minocycline: prominent Kerley B lines as a feature of positive re-challenge test, Jpn J Med, 29, (1990)
  • [10] Tada S., Kajimoto K., Sugimoto K., Et al., The cellular kinetics in BAL fluid of hypersensitivity pneumonitis and pulmonary function, Jpn J Allergology, 41, (1992)