EVALUATION OF TRICALCIUMPHOSPHATE HYDROXYAPATITE CEMENT FOR TOOTH REPLACEMENT - AN EXPERIMENTAL ANIMAL STUDY

被引：67

作者：

JANSEN, JA ^{[1
]}

DERUIJTER, JE ^{[1
]}

SCHAEKEN, HG ^{[1
]}

VANDERWAERDEN, JPCM ^{[1
]}

PLANELL, JA ^{[1
]}

DRIESSENS, FCM ^{[1
]}

机构：

[1] UNIV POLITECN CATALUNYA,DEPT CIENCIA MAT & ENGN MET,E-08028 BARCELONA,SPAIN

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1995年 / 6卷 / 11期

关键词：

D O I：

10.1007/BF00123447

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

calciumphosphate cement, consisting mainly of tricalciumphosphate (85% alpha-TCP and 15% beta-TCP), was inserted in 16 surgical defects created in the tibia of goats. X-ray diffraction (XRD) and energy dispersive spectroscopy (EDS) showed that after 3 months of implantation the alpha-TCP was transformed to hydroxyapatite (HA). Histological evaluation revealed that the presence of cement stimulated the ingrowth of bone compared with unfilled cavities. Active resorption and remodelling of cement particles was observed. The cement did not evoke an inflammatory reaction. At 6 months after implantation no further changes in the composition of the cement occurred. All remaining material was surrounded by mature bone.

引用

页码：653 / 657

页数：5

共 18 条

[1] DEVELOPMENT OF SOME CALCIUM-PHOSPHATE CEMENTS FROM COMBINATIONS OF ALPHA-TCP, MCPM AND CAO [J].

BERMUDEZ, O ;

BOLTONG, MG ;

DRIESSENS, FCM ;

PLANELL, JA .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 1994, 5 (03) :160-163

[2] LONG-TERM STUDY OF HYDROXYLAPATITE IMPLANTS IN CANINE ALVEOLAR BONE [J].

BOYNE, PJ ;

ROTHSTEIN, SS ;

GUMAER, KI ;

DROBECK, HP .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 1984, 42 (09) :589-594

[3] SKELETAL REPAIR BY IN-SITU FORMATION OF THE MINERAL PHASE OF BONE [J].

CONSTANTZ, BR ;

ISON, IC ;

FULMER, MT ;

POSER, RD ;

SMITH, ST ;

VANWAGONER, M ;

ROSS, J ;

GOLDSTEIN, SA ;

JUPITER, JB ;

ROSENTHAL, DI .

SCIENCE, 1995, 267 (5205) :1796-1799

[4] MACROPOROUS CALCIUM-PHOSPHATE CERAMIC FOR LONG-BONE SURGERY IN HUMANS AND DOGS - CLINICAL AND HISTOLOGICAL STUDY [J].

DACULSI, G ;

PASSUTI, N ;

MARTIN, S ;

DEUDON, C ;

LEGEROS, RZ ;

RAHER, S .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1990, 24 (03) :379-396

[5] 11-YEAR STUDY OF HYDROXYAPATITE IMPLANTS [J].

DENISSEN, HW ;

KALK, W ;

VELDHUIS, AAH ;

VANDENHOOFF, A .

JOURNAL OF PROSTHETIC DENTISTRY, 1989, 61 (06) :706-712

[6]

DENISSEN HW, 1980, CLIN PREV DENT, V2, P23

[7] FORMULATION AND SETTING TIMES OF SOME CALCIUM ORTHOPHOSPHATE CEMENTS - A PILOT-STUDY [J].

DRIESSENS, FCM ;

BOLTONG, MG ;

BERMUDEZ, O ;

PLANELL, JA .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 1993, 4 (05) :503-508

[8] CHARACTERIZATION OF CALCIUM-PHOSPHATE POWDERS BY ESCA AND EDXA [J].

KIESWETTER, K ;

BAUER, TW ;

BROWN, SA ;

VANLENTE, F ;

MERRITT, K .

BIOMATERIALS, 1994, 15 (03) :183-188

[9] BIODEGRADATION BEHAVIOR OF VARIOUS CALCIUM-PHOSPHATE MATERIALS IN BONE TISSUE [J].

KLEIN, CPAT ;

DRIESSEN, AA ;

DEGROOT, K ;

VANDENHOOFF, A .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1983, 17 (05) :769-784

[10] A NEW SAW TECHNIQUE IMPROVES PREPARATION OF BONE SECTIONS FOR LIGHT AND ELECTRON-MICROSCOPY [J].

KLEIN, CPAT ;

SAUREN, YMHF ;

MODDERMAN, WE ;

VANDERWAERDEN, JPCM .

JOURNAL OF APPLIED BIOMATERIALS, 1994, 5 (04) :369-373

← 1 2 →