RELATIVE HEPATOTOXICITY OF ORTHO-MONO AND META-MONO SUBSTITUTED THIOBENZAMIDES IN THE RAT

被引：9

作者：

CASHMAN, JR

PARIKH, KK

TRAIGER, GJ

HANZLIK, RP

机构：

[1] UNIV KANSAS,DEPT MED CHEM,LAWRENCE,KS 66045

[2] UNIV KANSAS,DEPT PHARMACOL & TOXICOL,LAWRENCE,KS 66045

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 1983年 / 45卷 / 03期

关键词：

D O I：

10.1016/0009-2797(83)90080-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：341 / 347

页数：7

共 18 条

[1]

AMMON R, 1967, ARZNEI-FORSCHUNG, V17, P521

[2] MICROSOMAL OXIDATION OF THIOBENZAMIDE - A PHOTOMETRIC ASSAY FOR THE FLAVIN-CONTAINING MONO-OXYGENASE [J].

CASHMAN, JR ;

HANZLIK, RP .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 98 (01) :147-153

[3] PNEUMOTOXIC EFFECTS OF THIOBENZAMIDE DERIVATIVES [J].

CASHMAN, JR ;

TRAIGER, GJ ;

HANZLIK, RP .

TOXICOLOGY, 1982, 23 (01) :85-93

[4] OXIDATION AND OTHER REACTIONS OF THIOBENZAMIDE DERIVATIVES OF RELEVANCE TO THEIR HEPATOTOXICITY [J].

CASHMAN, JR ;

HANZLIK, RP .

JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (24) :4645-4650

[5]

CASHMAN JR, 1982, THESIS U KANSAS

[6] THE HEPATOTOXICITY OF THIOBENZAMIDE-S-OXIDE [J].

CHIELI, E ;

MALVALDI, G ;

SEGNINI, D .

TOXICOLOGY LETTERS, 1980, 7 (02) :175-180

[7]

DRYOFF MC, 1981, CANCER RES, V41, P3430

[8]

FAIRFULL AES, 1952, J CHEM SOC, P742

[9] COMPARATIVE METABOLISM OF 2,6-DICHLOROTHIOBENZAMIDE (PREFIX) AND 2,6-DICHLOROBENZONITRILE IN DOG AND RAT [J].

GRIFFITHS, MH ;

MOSS, JA ;

ROSE, JA ;

HATHWAY, DE .

BIOCHEMICAL JOURNAL, 1966, 98 (03) :770-+

[10] SUBSTITUENT EFFECTS ON THE HEPATOTOXICITY OF THIOBENZAMIDE DERIVATIVES IN THE RAT [J].

HANZLIK, RP ;

VYAS, KP ;

TRAIGER, GJ .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1978, 46 (03) :685-694

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