ANTIMALARIAL ACTIVITY OF SOME NOVEL DERIVATIVES OF 2,4-DIAMINO-5-(PARA-CHLOROPHENYL)-6-ETHYLPYRIMIDINE (PYRIMETHAMINE)

被引：5

作者：

REES, RWA ^{[1
]}

CHAI, SY ^{[1
]}

WINKLEY, MW ^{[1
]}

RUSSELL, PB ^{[1
]}

机构：

[1] WYETH LABS INC, DIV RES, PHILADELPHIA, PA 19101 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1976年 / 19卷 / 05期

关键词：

D O I：

10.1021/jm00227a029

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：723 / 725

页数：3

共 7 条

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[2] ANALOGS OF TETRAHYDROFOLIC ACID .26. SYNTHESIS OF SOME 5-ARYL AND 5-ARALKYL PYRIMIDINE-6-CARBOXYLIC ACIDS AND THEIR EFFECT ON DIHYDROFOLIC REDUCTASE AND THYMIDYLATE SYNTHETASE [J].

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JORDAAN, JH .

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[3] 2-4-DIAMINOPYRIMIDINES - A NEW SERIES OF ANTIMALARIALS [J].

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GOODWIN, LG ;

HITCHINGS, GH ;

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RUSSELL, PB .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1951, 6 (02) :185-200

[4]

GREENSPAN G, UNPUBLISHED RESULTS

[5] 2,4,7-TRIAMINO-6-ORTHO-SUBSTITUTED ARYLPTERIDINES . A NEW SERIES OF POTENT ANTIMALARIAL AGENTS [J].

OSDENE, TS ;

RUSSELL, PB ;

RANE, L .

JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (03) :431-&

[6] ANTIMALARIAL ACTIVITIES OF SOME 3,5-DIAMINO-AS-TRIAZINE DERIVATIVES [J].

REES, RWA ;

RUSSELL, PB ;

BRIGHT, RE ;

FOELL, TJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (08) :859-&

[7] 2,4-DIAMINOPYRIMIDINES AS ANTIMALARIALS .3. 5-ARYL DERIVATIVES [J].

RUSSELL, PB ;

HITCHINGS, GH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1951, 73 (08) :3763-3770

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