MASS-SPECTRAL STUDIES .14. TLC-CIMS - A HIGHLY EFFICIENT MASS-SPECTRAL TECHNIQUE FOR SYNTHETIC ORGANIC CHEMISTS

被引：7

作者：

BOSE, AK

TABEI, K

RAJU, VS

机构：

[1] Department of Chemistry, Chemical Engineering Stevens Institute of Technology, Hoboken

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(00)88847-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A combination of thin layer chromatography with chemical ionization mass spectrometry has been developed for analyzing mixtures such as crude reaction products from a synthesis. Direct transfer of silica gel with adsorbed compounds from a TLC spot to a solids probe is made by using a Carbowax 20M pellet. Additional structural information can be generated by performing TLC-CIMS experiments after in situ ozonation of TLC spot material. This rapid method of analysis is valuable for monitoring highly accelerated organic reactions in a microwave oven. © 1990.

引用

页码：1661 / 1664

页数：4

共 12 条

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[J]. JOURNAL OF NATURAL PRODUCTS, 1989, 52 (03): : 534 - 546

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