ENANTIOMERIC SEPARATION OF RACEMIC HYDROPEROXIDES AND RELATED ALCOHOLS

被引：20

作者：

KUNATH, A ^{[1
]}

HOFT, E ^{[1
]}

HAMANN, HJ ^{[1
]}

WAGNER, J ^{[1
]}

机构：

[1] HUMBOLDT UNIV,INST BIOORGAN CHEM,O-1040 BERLIN,GERMANY

来源：

JOURNAL OF CHROMATOGRAPHY | 1991年 / 588卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(91)85046-I

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Racemic hydroperoxides and alcohols were chromatographed on a chiral stationary phase consisting of cellulose tris(3,5-dimethylphenyl coated on macroporous silica using hexane-2-propanol mobile phases. It was found that the retention (k') and the stereoselectivity (alpha) of secondary and tertiary chiral hydroperoxides and related alcohols are influenced by both the ambient temperature and water saturation of the mobile phase. The results indicate that water saturation of the mobile phase leads to decreased k' values and increased alpha. Increasing the temperature causes a clear decrease in k' but only a slightly decrease in alpha.

引用

页码：352 / 355

页数：4

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