RESIDUAL PH(-) CELLS IN CHRONIC MYELOID-LEUKEMIA - DETECTION AND USEFULNESS

被引：1

作者：

CHANG, J

COUTINHO, LH

SANTOS, AMW

BRERETON, M

HARRISON, CJ

TESTA, NG

机构：

[1] Department of Experimental Hematology, Paterson Institute for Cancer Research, Christie Hospital, Manchester

来源：

STEM CELLS | 1993年 / 11卷

关键词：

CHRONIC MYELOID LEUKEMIA; LONG-TERM BONE MARROW CULTURE; AUTOLOGOUS BONE MARROW TRANSPLANTATION;

D O I：

10.1002/stem.5530110612

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Bone marrow cells from patients with chronic myeloid leukemia (CMI,) in in vitro long-term bone marrow culture (LTBMC) show an impaired survival of Philadelphia (Ph) positive cells and, in a proportion of patients, the emergence of Philadelphia negative hemopoiesis. The standard conditions of in vitro cultures provide optimal purging effect. Selected patients can now have autologous bone marrow transplants (ABMT) with in vitro purged cells.

引用

页码：59 / 61

页数：3

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