DOPAMINERGIC ACTIVITY IS REDUCED IN DIABETIC RATS

被引：63

作者：

SALLER, CF ^{[1
]}

机构：

[1] NIMH, CLIN SCI LAB, BETHESDA, MD 20205 USA

来源：

NEUROSCIENCE LETTERS | 1984年 / 49卷 / 03期

关键词：

D O I：

10.1016/0304-3940(84)90306-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Dopamine [DA] synthesis rates in synaptosomes prepared from the striata of alloxan-diabetic rats were considerably lower than in control preparations. Striatal DA metabolite levels, after an initial increase, were also reduced at 3 and 6 wk after alloxan administration. Dopaminergic functioning may be impaired in diabetic rats.

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页码：301 / 306

页数：6

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