EFFECT OF PESTICIDES ON THE LDH ACTIVITY AND ISOENZYME PATTERN OF CARP (CYPRINUS-CARPIO L) SERA

被引：42

作者：

ASZTALOS, B ^{[1
]}

NEMCSOK, J ^{[1
]}

机构：

[1] ATTILA JOZSEF UNIV, DEPT BIOCHEM, POB 533, H-6701 SZEGED, HUNGARY

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY | 1985年 / 82卷 / 01期

关键词：

D O I：

10.1016/0742-8413(85)90233-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Copper sulphate (CuSO4), paraquat (PQ) and methidation (MD) all caused tissue necrosis as demonstrated by increased levels of lactate dehydrogenase (LDH, EC. 1.1.1.27) in blood sera. 2. The main target of damage is shown by the isoenzymes appearing in the blood sera. 3. The CuSO4 treatment damaged mainly the heart and skeletal muscles. This is indicated by the increased LDH level and the M and H subunits appearing in the isoenzyme pattern of the serum. 4. PQ damaged first of al the gills and methidation had an effect on the skeletal muscles.

引用

页码：217 / 219

页数：3

共 16 条

[1] DISSOCIATION OF LACTATE DEHYDROGENASE INTO SUBUNITS WITH GUANIDINE HYDROCHLORIDE [J].

APPELLA, E ;

MARKERT, CL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1961, 6 (03) :171-&

[2]

BENEDECZKY I, 1984, Acta Universitatis Szegediensis Acta Biologica, V30, P107

[3] LYSOSOMAL ENHANCEMENT IN HEPATIC CELLS OF A TELEOST FISH INDUCED BY CADMIUM [J].

FERRI, S ;

MACHA, N .

CELL BIOLOGY INTERNATIONAL REPORTS, 1980, 4 (04) :357-363

[4] PARAQUAT POISONING - RECOVERY FROM RENAL AND PULMONARY DAMAGE [J].

FISHER, HK ;

HUMPHRIES, M ;

BAILS, R .

ANNALS OF INTERNAL MEDICINE, 1971, 75 (05) :731-+

[5]

HORVATH I, 1979, Acta Universitatis Szegediensis Acta Biologica, V25, P133

[6] THE FORMATION OF MIXED DISULFIDES IN RAT LUNG FOLLOWING PARAQUAT ADMINISTRATION - CORRELATION WITH CHANGES IN INTERMEDIARY METABOLISM [J].

KEELING, PL ;

SMITH, LL ;

ALDRIDGE, WN .

BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 716 (02) :249-257

[7]

KRISTOFFERSSON R, 1974, Annales Zoologici Fennici, V11, P220

[8] LACTATE DEHYDROGENASE ISOZYME PATTERNS OF FISH [J].

MARKERT, CL ;

FAULHABER, I .

JOURNAL OF EXPERIMENTAL ZOOLOGY, 1965, 159 (03) :319-+

[9] CHANGES IN BLOOD OF BROOK TROUT (SALVELINUS-FONTINALIS) AFTER SHORT-TERM AND LONG-TERM EXPOSURE TO COPPER [J].

MCKIM, JM ;

CHRISTENSEN, GM ;

HUNT, EP .

JOURNAL OF THE FISHERIES RESEARCH BOARD OF CANADA, 1970, 27 (10) :1883-+

[10] EFFECTS OF COPPER, ZINC AND PARAQUAT ON ACETYLCHOLINESTERASE ACTIVITY IN CARP (CYPRINUS-CARPIO L) [J].

NEMCSOK, J ;

NEMETH, A ;

BUZAS, Z ;

BOROSS, L .

AQUATIC TOXICOLOGY, 1984, 5 (01) :23-31

← 1 2 →