LIGAND RECEPTOR INTERACTIONS VIA HYDROGEN-BOND FORMATION - SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF PYRROLO AND PYRIDO ANALOGS OF THE CARDIOTONIC AGENT 7-HYDROXYCYCLINDOLE

被引：9

作者：

DIONNE, G ^{[1
]}

HUMBER, LG ^{[1
]}

ASSELIN, A ^{[1
]}

MCQUILLAN, J ^{[1
]}

TREASURYWALA, AM ^{[1
]}

机构：

[1] AYERST LABS RES INC, CN8000, PRINCETON, NJ 08540 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 08期

关键词：

D O I：

10.1021/jm00158a022

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1452 / 1457

页数：6

共 15 条

[1] INDOLE PHENOL BIOISOSTERISM - SYNTHESIS AND ANTIHYPERTENSIVE ACTIVITY OF A PYRROLO ANALOG OF LABETALOL [J].

ASSELIN, AA ;

HUMBER, LG ;

CROSILLA, D ;

OSHIRO, G ;

WOJDAN, A ;

GRIMES, D ;

HEASLIP, RJ ;

RIMELE, TJ ;

SHAW, CC .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (06) :1009-1015

[2] DRUG DESIGN VIA PHARMACOPHORE IDENTIFICATION - DOPAMINERGIC ACTIVITY OF 3H-BENZ[E]INDOL-8-AMINES AND THEIR MODE OF INTERACTION WITH THE DOPAMINE RECEPTOR [J].

ASSELIN, AA ;

HUMBER, LG ;

VOITH, K ;

METCALF, G .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (05) :648-654

[3] HEMODYNAMIC ASSESSMENT OF AMRINONE - NEW INOTROPIC AGENT [J].

BENOTTI, JR ;

GROSSMAN, W ;

BRAUNWALD, E ;

DAVOLOS, DD ;

ALOUSI, AA .

NEW ENGLAND JOURNAL OF MEDICINE, 1978, 299 (25) :1373-1377

[4] AMINO ACIDS .7. DL-BETA-AMINOADIPIC ACID - PREPARATION AND OXIDATION OF 2-ACETAMIDOCYCLOHEXANOLS, 3-ACETAMIDOCYCLOHEXANOLS AND 4-ACETAMIDOCYCLOHEXANOLS [J].

BILLMAN, JH ;

BUEHLER, JA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1953, 75 (06) :1345-1346

[5] CARCINOGENIC NITROGEN COMPOUNDS .32. SYNTHESIS OF NEW HIGHLY ACTIVE BENZOPYRIDOCARBAZOLES [J].

BUUHOI, NP ;

JACQUIGNON, P ;

PERIN, F .

JOURNAL OF THE CHEMICAL SOCIETY, 1962, (JAN) :146-&

[6] STEREOCHEMISTRY OF CYCLOHEXANE DERIVATIVES .7. 4-AMINOCYCLOHEXANOLS [J].

DELLA, EW ;

JEFFERIES, PR .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1961, 14 (04) :610-&

[7] NEW CARDIOTONIC AGENTS - SEARCH FOR DIGITALIS SUBSTITUTE [J].

FARAH, AE ;

ALOUSI, AA .

LIFE SCIENCES, 1978, 22 (13-1) :1139-1147

[8] SYNTHESIS OF 7-AZABICYCLO 2.2.1!HEPTANE, EXO-2-CHLORO-7-AZABICYCLO 2.2.1!HEPTANE, AND DERIVATIVES [J].

FRASER, RR ;

SWINGLE, RB .

CANADIAN JOURNAL OF CHEMISTRY, 1970, 48 (13) :2065-&

[9] PYRIDYL-ACETYLENE UND CHINOLYL-ACETYLENE .1. DARSTELLUNG UND EIGENSCHAFTEN DER PYRIDYL-ACETYLENE UND CHINOLYL-ACETYLENE [J].

HAUG, U ;

FURST, H .

CHEMISCHE BERICHTE-RECUEIL, 1960, 93 (03) :593-598

[10] CHROMIC ACID OXIDATION OF CYCLOHEXANOLS TO CYCLOHEXANONES [J].

HUSSEY, AS ;

BAKER, RH .

JOURNAL OF ORGANIC CHEMISTRY, 1960, 25 (08) :1434-1434

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