IDENTIFICATION OF 3-METHYL-2-THIOHYDANTOIN, A METABOLITE OF CARBIMAZZOLE, IN MAN

被引：14

作者：

SKELLERN, GG

KNIGHT, BI

LUMAN, FM

STENLAKE, JB

MCLARTY, DG

HOOPER, MJ

机构：

[1] UNIV STRATHCLYDE,DEPT PHARMACEUT CHEM,DRUG METAB RES UNIT,GLASGOW G1 1XW,SCOTLAND

[2] WESTERN INFIRM,GARDINER INST,DEPT MED,GLASGOW G11 6NT,SCOTLAND

[3] STOBHILL GEN HOSP,DEPT MAT MED,GLASGOW G21 3UW,SCOTLAND

来源：

XENOBIOTICA | 1977年 / 7卷 / 04期

关键词：

D O I：

10.3109/00498257709035782

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：247 / 253

页数：7

共 14 条

[1] METABOLISM OF 35S-LABELLED ANTITHYROID DRUGS IN MAN [J].

ALEXANDER, WD ;

EVANS, V ;

MACAULAY, A ;

GALLAGHER, TF ;

LONDONO, J .

BMJ-BRITISH MEDICAL JOURNAL, 1969, 2 (5652) :290-+

[2] MASS SPECTROMETRY IN STRUCTURAL AND STEREOCHEMICAL PROBLEMS .204. SPECTRA OF HYDANTOINS .2. ELECTRON IMPACT INDUCED FRAGMENTATION OF SOME SUBSTITUTED HYDANTOINS [J].

CORRAL, RA ;

ORAZI, OO ;

DUFFIELD, AM ;

DJERASSI, C .

ORGANIC MASS SPECTROMETRY, 1971, 5 (05) :551-&

[3] THIOHYDANTOINS .1. IONISATION AND ULTRAVIOLET ABSORPTION [J].

EDWARD, JT ;

NIELSEN, S .

JOURNAL OF THE CHEMICAL SOCIETY, 1957, (DEC) :5075-5079

[4] SEQUENCE ANALYSIS OF COMPLEX PROTEIN MIXTURES BY ISOTOPE DILUTION AND MASS SPECTROMETRY [J].

FAIRWELL, T ;

BARNES, WT ;

RICHARDS, FF ;

LOVINS, RE .

BIOCHEMISTRY, 1970, 9 (11) :2260-+

[5] ANTITHYROID ACTIVITY OF THIOHYDANTOINS [J].

KILPATRICK, R ;

ELMORE, DT ;

WOOD, DR .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1958, 13 (03) :350-356

[6] THYROID ACCUMULATION, OXIDATION AND METABOLIC FATE OF S-35-METHIMAZOLE IN RAT [J].

MARCHANT, B ;

ALEXANDE.WD .

ENDOCRINOLOGY, 1972, 91 (03) :747-&

[7] BILIARY-EXCRETION OF S-35-LABELED PROPYLTHIOURACIL, METHIMAZOLE AND CARBIMAZOLE IN UNTREATED AND PENTOBARBITONE PRETREATED RATS [J].

PAPAPETROU, PD ;

ALEXANDER, WD ;

GAVRAS, H ;

MARCHANT, B .

BIOCHEMICAL PHARMACOLOGY, 1972, 21 (03) :363-+

[8] S-OXIDATION OF THIOUREYLENES CATALYZED BY A MICROSOMAL FLAVOPROTEIN MIXED-FUNCTION OXIDASE [J].

POULSEN, LL ;

HYSLOP, RM ;

ZIEGLER, DM .

BIOCHEMICAL PHARMACOLOGY, 1974, 23 (24) :3431-3440

[9] A NEW ROUTE TO IMIDAZOLE-2-THIONES FROM 2-THIOHYDANTOINS [J].

SCOTT, JE ;

HENDERSON, G .

BIOCHEMICAL JOURNAL, 1968, 109 (02) :209-+

[10] ANTITHYROID SUBSTANCES .2. SOME MERCAPTOGLYOXALINES, MERCAPTOTHIAZOLES AND THIOHYDANTOINS [J].

SEARLE, CE ;

LAWSON, A ;

MORLEY, HV .

BIOCHEMICAL JOURNAL, 1951, 49 (01) :125-128

← 1 2 →