THE ENANTIOSELECTIVE GLUCURONIDATION OF MORPHINE IN RATS AND HUMANS - EVIDENCE FOR THE INVOLVEMENT OF MORE THAN ONE UDP-GLUCURONOSYLTRANSFERASE ISOENZYME

被引：96

作者：

COUGHTRIE, MWH

ASK, B

RANE, A

BURCHELL, B

HUME, R

机构：

[1] UNIV EDINBURGH,DEPT CHILD LIFE & HLTH,EDINBURGH EH8 9YL,MIDLOTHIAN,SCOTLAND

[2] UNIV DUNDEE,INST MED SCI,DEPT BIOCHEM,DUNDEE DD1 4HN,SCOTLAND

[3] UNIV UPPSALA HOSP,DIV CLIN PHARMACOL,S-75014 UPPSALA,SWEDEN

来源：

BIOCHEMICAL PHARMACOLOGY | 1989年 / 38卷 / 19期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0006-2952(89)90625-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：3273 / 3280

页数：8

相关论文

共 21 条

[1] PURIFICATION OF RAT-LIVER MICROSOMAL UDP-GLUCURONYLTRANSFERASE - SEPARATION OF 2 ENZYME FORMS INDUCIBLE BY 3-METHYLCHOLANTHRENE OR PHENOBARBITAL
BOCK, KW
JOSTING, D
LILIENBLUM, W
PFEIL, H
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1979, 98 (01): : 19 - 26
[2] BOCK KW, 1984, DRUG METAB DISPOS, V12, P93
[3] CORNELIUS CE, 1972, AM J PATHOL, V69, P369
[4] CORSER RB, 1987, FEBS LETT, V213, P445
[5] COUGHTRIE MWH, 1988, MOL PHARMACOL, V34, P729
[6] COUGHTRIE MWH, 1987, MOL PHARMACOL, V31, P585
[7] Dutton G. J. F., 1980, GLUCURONIDATION DRUG
[8] COMPARISON IN DIFFERENT SPECIES OF BILIARY BILIRUBIN-IXALPHA CONJUGATES WITH ACTIVITIES OF HEPATIC AND RENAL BILIRUBIN-IXALPHA-URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASES
FEVERY, J
VANDEVIJVER, M
MICHIELS, R
HEIRWEGH, KPM
[J]. BIOCHEMICAL JOURNAL, 1977, 164 (03) : 737 - 746
[9] FOURNELGIGLEUX S, IN PRESS DRUG METAB
[10] Gawronska-Szklarz B., 1985, ADV GLUCURONIDE CONJ, P335