CHEMOENZYMATIC ASYMMETRIC-SYNTHESIS OF AMINO-ACIDS - ENANTIOSELECTIVE HYDROLYZES OF 2-PHENYL-OXAZOLIN-5-ONES

被引:55
作者
GU, RL [1 ]
LEE, IS [1 ]
SIH, CJ [1 ]
机构
[1] UNIV WISCONSIN,SCH PHARM,MADISON,WI 53706
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0040-4039(92)88111-H
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Porcine pancreatic lipase and the lipase of Aspergillus niger catalyze the enantioselective hydrolysis of a series of 4-substituted-2-phenyl-oxazolin-5-ones to yield optically active (S)- and (R)-N-benzoyl amino acids respectively.
引用
收藏
页码:1953 / 1956
页数:4
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