REGIOSELECTIVITY AND STEREOSELECTIVITY OF AN ASYMMETRIC LACTONE - STRUCTURAL-ANALYSIS USING NUCLEAR OVERHAUSER EFFECTS AND MOLECULAR MODELING

被引：6

作者：

BERRIER, C ^{[1
]}

BONNAUD, B ^{[1
]}

PATOISEAU, JF ^{[1
]}

BIGG, D ^{[1
]}

机构：

[1] CTR RECH PIERRE FABRE MEDICAMENT, F-81106 CASTRES, FRANCE

来源：

TETRAHEDRON | 1991年 / 47卷 / 46期

关键词：

D O I：

10.1016/S0040-4020(01)91029-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lactone I is an important intermediate in the synthesis of compounds with therapeutic properties. In order to prepare new derivatives, reactivity of I has been studied. Cis and trans conformations of both 2,3-diphenyl-1-oxabicyclo [3,1,0] hexanes VIIIa and VIIIb were assigned by H-1 N.M.R spectroscopy using NOE DIFF experiments, and molecular modelling.

引用

页码：9629 / 9640

页数：12

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