AN ANTIFUNGAL NAPHTHOQUINONE, XANTHONES AND SECOIRIDOIDS FROM SWERTIA-CALYCINA

被引：76

作者：

RODRIGUEZ, S

WOLFENDER, JL

HAKIZAMUNGU, E

HOSTETTMANN, K

机构：

[1] UNIV LAUSANNE,INST PHARMACOGNOSIE & PHYTOCHIM,CH-1015 LAUSANNE,SWITZERLAND

[2] INST RECH SCI & TECHNOL,CURPHAMETRA,BUTARE,RWANDA

来源：

PLANTA MEDICA | 1995年 / 61卷 / 04期

关键词：

D O I：

10.1055/s-2006-958102

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity has been isolated and identified as 2-methoxy-1,4-naphthoquinone. It is the first naphthoquinone to be described in Gentianaceae species. LC-UV and LC-TSP-MS analysis of the crude extracts of Swertia calycina also allowed on-line identification of six known xanthones and secoiridoids.

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页码：362 / 364

页数：3

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