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ALVEOLAR RHABDOMYOSARCOMA WITH DEL(13Q14)

被引：10
作者：
HARRISON, CJ
JOHNSON, PRE
YIN, JAL
BHAVNANI, M
机构：
[1] MANCHESTER ROYAL INFIRM,DEPT CLIN HAEMATOL,OXFORD RD,MANCHESTER M13 9WL,LANCS,ENGLAND
[2] CHRISTIE HOSP & HOLT RADIUM INST,PATERSON LAB,NW REG CYTOGENET SERV,MANCHESTER M20 9BX,LANCS,ENGLAND
[3] ROYAL ALBERT EDWARDS INFIRM,WIGAN,ENGLAND
来源：
CANCER GENETICS AND CYTOGENETICS | 1991年 / 55卷 / 02期
关键词：
D O I：
10.1016/0165-4608(91)90086-A
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We report a case of disseminated alveolar rhabdomyosarcoma, where chromosome analysis showed a deletion of chromosome 13(q14). This breakpoint is involved in the t(2;13)(q37;q14) previously reported in cases of rhabdomyosarcoma, but this is the first reported case in whom this deletion occurs without involvement of chromosome 2. The possible oncogenic role of the retinoblastoma (RB1) gene located at the breakpoint is discussed.
引用
收藏
页码：257 / 259
页数：3
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