METABOLISM OF COCAINE AND NORCOCAINE TO N-HYDROXYNORCOCAINE

被引：45

作者：

SHUSTER, L

CASEY, E

WELANKIWAR, SS

机构：

来源：

BIOCHEMICAL PHARMACOLOGY | 1983年 / 32卷 / 20期

关键词：

D O I：

10.1016/0006-2952(83)90247-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：3045 / 3051

页数：7

共 17 条

[1] BIOLOGICAL EFFECTS OF COCAINE DERIVATIVES .1. IMPROVED SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NORCOCAINE [J].

BORNE, RF ;

BEDFORD, JA ;

BUELKE, JL ;

CRAIG, CB ;

HARDIN, TC ;

KIBBE, AH ;

WILSON, MC .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1977, 66 (01) :119-120

[2]

EVANS MA, 1981, FED PROC, V40, P638

[3]

HINSON JA, 1976, DRUG METAB DISPOS, V4, P430

[4]

HINSON JA, 1975, MOL PHARMACOL, V11, P462

[5] STUDIES ON THE MECHANISM OF HEPATIC MICROSOMAL N-OXIDE FORMATION - N-OXIDATION OF NN-DIMETHYLANILINE BY A RECONSTITUTED RABBIT LIVER MICROSOMAL CYTOCHROME P-448 ENZYME-SYSTEM [J].

HLAVICA, P ;

HULSMANN, S .

BIOCHEMICAL JOURNAL, 1979, 182 (01) :109-116

[6] INVOLVEMENT OF FAD-CONTAINING MONO-OXYGENASE IN COCAINE-INDUCED HEPATOTOXICITY [J].

KLOSS, MW ;

CAVAGNARO, J ;

ROSEN, GM ;

RAUCKMAN, EJ .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1982, 64 (01) :88-93

[7] STABILITY OF DRUG METABOLISING ENZYMES OF LIVER MICROSOMAL PREPARATIONS [J].

LEADBEATER, L ;

DAVIES, DR .

BIOCHEMICAL PHARMACOLOGY, 1964, 13 (12) :1607-+

[8] EFFECT OF STORAGE OF FROZEN LIVER MICROSOMAL PREPARATIONS ON HYDROXYLATION OF TESTOSTERONE AND PENTOBARBITAL AND N-DEMETHYLATION OF ETHYLMORPHINE [J].

LEVIN, W ;

ALVARES, A ;

JACOBSON, M ;

KUNTZMAN, R .

BIOCHEMICAL PHARMACOLOGY, 1969, 18 (04) :883-&

[9]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[10] LACK OF EVIDENCE FOR N-HYDROXYACETAMINOPHEN AS A REACTIVE METABOLITE OF ACETAMINOPHEN INVITRO [J].

NELSON, SD ;

FORTE, AJ ;

DAHLIN, DC .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (11) :1617-1620

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