THE ACUTE EFFECTS OF CAFFEINE, COCAINE AND D-AMPHETAMINE ON THE REPEATED ACQUISITION RESPONDING OF PIGEONS

被引：12

作者：

EVANS, EB ^{[1
]}

WENGER, GR ^{[1
]}

机构：

[1] UNIV ARKANSAS MED SCI HOSP,DEPT PHARMACOL & TOXICOL,MAIL SLOT 611,4301 W MARKHAM ST,LITTLE ROCK,AR 72205

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1990年 / 35卷 / 03期

关键词：

Behavior; Caffeine; Cocaine; d-amphetamine; Learning; Pigeon; Repeated acquisition;

D O I：

10.1016/0091-3057(90)90300-7

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The acute effects of caffeine, cocaine and d-amphetamine on the repeated acquisition of a four-response chain were investigated in pigeons. Subjects responded on three response keys under different predetermined sequences. Food was presented upon the completion of the four-response sequence under a fixed-ratio schedule. Incorrect responses resulted in a five-second timeout. No consistent increases in within session percent correct were observed following caffeine or d-amphetamine administration. However, cocaine (1.0 mg/kg) did produce consistent increases in within session percent correct. At higher doses of cocaine, d-amphetamine and caffeine the effects observed were similar in that there was a decrease in response rate and percent correct. The drugs did differ in the dose (potency) which decreased response rate and percent correct. Following all three drugs if percent correct was decreased there was a concurrent decrease in response rate. © 1990.

引用

页码：631 / 636

页数：6

共 22 条

[1] REPEATED ACQUISITION OF BEHAVIORAL CHAINS [J].