VOLUME OF DISTRIBUTION TERMS FOR A DRUG (CEFTRIAXONE) EXHIBITING CONCENTRATION-DEPENDENT PROTEIN-BINDING .1. THEORETICAL CONSIDERATIONS

被引：50

作者：

MCNAMARA, PJ

GIBALDI, M

STOECKEL, K

机构：

[1] UNIV WASHINGTON,SCH PHARM,SEATTLE,WA 98195

[2] F HOFFMANN LA ROCHE & CO LTD,DEPT BIOL PHARMACEUT RES,CH-4002 BASEL,SWITZERLAND

来源：

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY | 1983年 / 25卷 / 03期

关键词：

D O I：

10.1007/BF01037955

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：399 / 405

页数：7

共 18 条

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[7] ACCUMULATION KINETICS OF DRUGS WITH NON-LINEAR PLASMA-PROTEIN AND TISSUE BINDING CHARACTERISTICS [J].

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[8] FRACTION UN-BOUND IN INTERSTITIAL FLUID [J].

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[9] VOLUME OF DISTRIBUTION TERMS FOR A DRUG (CEFTRIAXONE) EXHIBITING CONCENTRATION-DEPENDENT PROTEIN-BINDING .2. PHYSIOLOGICAL SIGNIFICANCE [J].

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EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 25 (03) :407-412

[10] EFFECT OF PLASMA-PROTEIN AND TISSUE BINDING ON THE TIME COURSE OF DRUG CONCENTRATION IN PLASMA [J].

MCNAMARA, PJ ;

LEVY, G ;

GIBALDI, M .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1979, 7 (02) :195-206

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