SYNTHESIS, REACTIVITY, AND BIOACTIVITY OF AVERMECTIN-B1-3,4-OXIDE

被引：17

作者：

BLIZZARD, TA

MROZIK, H

PREISER, FA

FISHER, MH

机构：

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 35期

关键词：

D O I：

10.1016/S0040-4039(00)97779-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Avermectin B1-3,4-oxide (2) has been synthesized from avermectin B1 (1). While epoxide 2 is comparable to avermectin B1 in bioactivity, opening of the epoxide leads to derivatives which are substantially less bioactive. © 1990.

引用

页码：4965 / 4968

页数：4

共 13 条

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