THE PREPARATION OF 5-SUBSTITUTED THIENO[2,3-B]FURAN-2-SULFONAMIDES

被引：2

作者：

HARTMAN, GD

HALCZENKO, W

PRUGH, JD

WILLIAMS, TM

机构：

[1] Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 03期

关键词：

D O I：

10.1002/jhet.5570270336

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthetic route is reported for the preparation of thieno[2,3‐e]furan‐2‐sulfonamides bearing oxygenated functionality at C‐5. The method employs conversion of furan‐3‐carboxaldehyde to an intermediate that, in the key step, undergoes facile cyclodehydration to the fused [5,5] heterocycle under mild Knoevenagel conditions. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：679 / 682

页数：4

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