THERAPEUTIC TIME WINDOW AND DOSE-RESPONSE OF THE BENEFICIAL-EFFECTS OF KETAMINE IN EXPERIMENTAL HEAD-INJURY

被引:87
作者
SHAPIRA, Y
LAM, AM
ENG, CC
LAOHAPRASIT, V
MICHEL, M
机构
[1] UNIV WASHINGTON,HARBORVIEW MED CTR,DEPT ANESTHESIOL,SEATTLE,WA 98104
[2] UNIV WASHINGTON,DEPT ANESTHESIOL,SEATTLE,WA 98195
[3] UNIV WASHINGTON,DEPT NEUROL SURG,SEATTLE,WA 98195
[4] BEN GURION UNIV NEGEV,SOROKA MED CTR,DEPT ANESTHESIOL,IL-84105 BEER SHEVA,ISRAEL
关键词
AMINO ACIDS; N-METHYL-D-ASPARTATE; BRAIN INJURIES; RATS;
D O I
10.1161/01.STR.25.8.1637
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and Purpose The aim of this study was to determine the time and dose response of the therapeutic effects of the N-methyl-D-aspartate receptor antagonist ketamine in experimental head injury.
引用
收藏
页码:1637 / 1643
页数:7
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