AUTORADIOGRAPHIC LOCALIZATION OF MAS PROTOONCOGENE MESSENGER-RNA IN ADULT-RAT BRAIN USING INSITU HYBRIDIZATION

被引:62
作者
BUNNEMANN, B
FUXE, K
METZGER, R
MULLINS, J
JACKSON, TR
HANLEY, MR
GANTEN, D
机构
[1] KAROLINSKA INST, DEPT HISTOL & NEUROBIOL, S-14104 HUDDINGE, SWEDEN
[2] UNIV HEIDELBERG, DEPT PHARMACOL, W-6900 HEIDELBERG, GERMANY
[3] MRC, MOLEC NEUROBIOL UNIT, CAMBRIDGE, ENGLAND
[4] MRC, MOLEC BIOL LAB, CAMBRIDGE CB2 2QH, ENGLAND
关键词
Angiotensin peptide; In situ hybridization; mas proto-oncogene; Rat;
D O I
10.1016/0304-3940(90)90063-F
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The cellular localization and the distribution of the mas proto-oncogene/angiotensin receptor mRNA have been studied in the male rat brain using in situ hybridization with radiolabelled mas cRNA probes. Neuronal cell populations in the forebrain were selectively labelled. A strong specific labelling was demonstrated in the dentate gyrus, the CA3 and CA4 areas of the hippocampus, the olfactory tubercle (medial part), the piriform cortex and the olfactory bulb, while a weak to moderate labelling was present all over the neocortex and especially in the frontal lobe. © 1990.
引用
收藏
页码:147 / 153
页数:7
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