PALLADIUM-CATALYZED REACTIONS IN AQUEOUS-MEDIA - AN EFFICIENT REMOVAL OF ALLYLOXYCARBONYL PROTECTING GROUP FROM OXYGEN AND NITROGEN

被引：51

作者：

GENET, JP ^{[1
]}

BLART, E ^{[1
]}

SAVIGNAC, M ^{[1
]}

LEMEUNE, S ^{[1
]}

PARIS, JM ^{[1
]}

机构：

[1] RHONE POULENC RORER,CTR RECH VITRY ALFORTVILLE,F-94403 VITRY,FRANCE

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 26期

关键词：

DEPROTECTION OF ALLYLOXY CARBONYL; SULFONATED TRIPHENYL PHOSPHINE (TPPTS); PALLADIUM AQUEOUS REACTIONS;

D O I：

10.1016/S0040-4039(00)60524-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Allyloxycarbonyl (Alloc) moiety can be removed smoothly and selectively in good yield (70-99%) from allylic esters, carbamates and carbonates by aqueous Pd (0) catalyzed allyl transfer to diethylamine as the accepting nucleophile. The method has been successfully used for deprotection of a wide range of secondary amines.

引用

页码：4189 / 4192

页数：4

共 28 条

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