TOWARD BIOMIMETIC SENSORS - A FLUORESCENT ARTIFICIAL MACROCYCLOPHANIC RECEPTOR FOR THE QUANTIFICATION OF ZN(II)

被引：7

作者：

CORDIER, D

DUMAINEBOUAZIZ, M

COULET, PR

机构：

[1] Laboratoire de Genie Enzymatique, URA 1535 CNRS - Universite Lyon 1, 69622, Villeurbanne Cedex, CPE- ESCIL

来源：

ANALYTICAL LETTERS | 1995年 / 28卷 / 06期

关键词：

FLUORESCENT ARTIFICIAL RECEPTOR; MACROCYCLOPHANE; METAL IONS BINDING; ZINC QUANTIFICATION;

D O I：

10.1080/00032719508002671

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A fluorescent artificial receptor previously synthesized in our group, is shown to be able to bind metal ions after dimerization. The monomer is a urea macrocyclophane: (13,21-Bis(methoxycarbonyl)-1,9,17-trioxo-2,8,16,18-tetraaza[9.3]metaorthocyclophane. The dimer is used to quantify Zn(II) through the fluorescence signal change observed upon complexation. This change can be related either to the decrease of the monomer or to the increase of the dimer forms. The response is linear for a Zn(II) concentration range between 5 and 50 mu M. Specificity for Zn(II), examplified by comparison with Cd(II), was found acceptable.

引用

页码：959 / 969

页数：11

共 8 条

[1]

Blum L.J., 1991, BIOSENSOR PRINCIPLES

[2]

CORDIER D, 1994, J CHEM SOC P2, V4, P891

[3]

Cotton FA., 1988, ADV INORG CHEM, V5

[4] ELECTROCHEMICAL AND FIBER OPTIC BIOSENSORS FOR HIGHLY SELECTIVE MOLECULAR TARGETING [J].